The Kratom Herald

Mitragyna Speciosa News And Information

Anyone Thinking Of Abusing Immodium (Loperamide) Due To A Lack Of Painkiller Availability Should Use Kratom Instead, Since Kratom Is Much Safer And Far Less Addictive

loperamide abuse

Yesterday I posted an article on The Kratom Herald about how Kratom is as effective as Immodium when it comes to anti-diarrheal effects, and this reminded me that Immodium (Loperamide) can actually cause major health problems when people abuse it, so I am writing this article to warn opioid users not to touch Immodium.

It may come as a shock that over the counter (OTC) Immodium can be abused, but the fact of the matter is that Immodium actually contains the synthetic opioid Loperamide. Loperamide is unscheduled and available OTC despite being a synthetic opioid, and notably Loperamide was a scheduled substance until 1988.

The reason that Loperamide was moved from Schedule V to OTC is that the drug company which was producing it presented evidence that it does not readily cross the blood-brain barrier, and also claimed that Loperamide is not readily absorbed in the gut.

However, plenty of people have tried to get high on Loperamide anyways via taking megadoses or using potentiators which help Loperamide to cross the blood-brain barrier.

Specifically, the standard Loperamide dose is 2 mg, but people who are trying to get high on Loperamide may take anywhere from 20 mg up to hundreds of mg, and in some cases this leads to strong opioid feelings of euphoria, warmth, painkilling, etc. Reports about such Loperamide megadosing can be read on Erowid

Also, a scientific study found that taking P-glycoprotein inhibitors such as quinidine or quinine, which is commonly found in tonic water, significantly increases the capability of Loperamide to cross the blood-brain barrier and leads to opiate-induced respiratory depression. Due to this study, numerous people have drank tonic water with Loperamide in an attempt to get high.

Zooming out, there are other reasons that people are using Loperamide besides trying to get high. If a pain patient is cut off from their prescription pain killers suddenly and is facing withdrawal, Loperamide may seem like a good option, since it is well-known that Loperamide alleviates most physical symptoms of opiate withdrawal. Indeed, Loperamide is sometimes referred to as ‘poor man’s Methadone’. 

Unfortunately, Loperamide is ultimately just as addictive as the other synthetic opioids and opiates, and there are numerous subjective reports across the internet of people getting heavily addicted to Loperamide, to the point where they have to take hundreds of Loperamide pills per day or they will go into severe opioid withdrawal.

Thus, although people may seek out Loperamide as a way to manage opioid withdrawal or to get high on opioids in an alternative way, in the end Loperamide is just as much of a trap as the other synthetic opioids and opiates.

Even worse, at the extremely high doses of Loperamide required to feel opioid effects, cardiotoxicity is a problem, and people have dropped dead from megadosing Loperamide. Further, just like with other synthetic opioids, a Loperamide overdose can lead to death due to respiratory suppression, especially if combined with other sedatives.

Zooming out, it is clear that anyone who is considering abusing or already abusing Loperamide should switch to Kratom. This is because Kratom can effectively relieve opiate withdrawal, Kratom lacks addiction potential and causes little to no physiological withdrawal symptoms, Kratom provides a solid boost of euphoria, stress/anxiety-relief, and pain relief, and there has never been a scientifically proven Kratom death in history.

Simply, Loperamide is not very effective and highly addictive and dangerous, while Kratom is very effective, relatively non-addictive, and totally safe. Therefore, people seeking an alternative and legal opioid should choose Kratom instead of Loperamide.