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Scientific Study Finds That Kratom Has Insulin-Like Action, And Therefore Kratom Has Anti-Diabetic Properties

Kratom has been used since ancient times in Thailand as a treatment for diabetes, and apparently it’s been quite successful as an anti-diabetes medicine since Kratom continues to be used for that purpose in Thailand to this day. A scientific study titled ‘Study on glucose transport in muscle cells by extracts from Mitragyna speciosa (Korth) and mitragynine‘ sought to confirm if Kratom really has anti-diabetic properties, and ultimately found that Kratom has insulin-like effects.

For starters, diabetes is caused by the body being overwhelmed with sugar and not producing enough natural insulin, which leads to an overdose of sugar throughout the body, which leads to extremely bad complications and is deadly long term. In order to combat this, patients are treated with insulin injections in order to bring blood sugar levels under control, but not even insulin is enough to prevent bad effects from diabetes damage long term.

The scientists who conducted this study did experiments with muscle cells and various forms of Kratom, in order to confirm if Kratom really has anti-diabetic effects, and if so, the underlying mechanisms responsible for these effects.

It was found that full spectrum Kratom extract and isolated Mitragynine stimulated the uptake of glucose, which is a critical property of anti-diabetic medications like insulin. Indeed, once again, the whole point of insulin is to increase the uptake of sugar (glucose) in order to bring sugar levels in the body back to normal.

The scientists even say that Kratom has a similar effect to insulin. Further, it was found that combining Kratom with insulin leads to even more powerful glucose uptake than insulin alone.

The scientists dived deeper into why this is the case, and found that Kratom reduces glucose via similar mechanisms to insulin. Although the science is complex, it comes down to Kratom interacts with key enzymes which stimulate glucose uptake. One specific example is that Kratom interacts with GLUT1 in a way which increases the amount of cell surface transporters and therefore increases glucose uptake. Also, Kratom changes the distribution of GLUT4 across the plasma membrane, also increasing glucose uptake.

Another important note is that the scientists found full spectrum Kratom has more anti-diabetic effects than Mitragynine alone, indicating that multiple alkaloids are involved with Kratom’s anti-diabetic effects, and therefore natural/full spectrum Kratom is the most effective.

Thus, scientists have confirmed that Kratom has anti-diabetic properties, which is something that has been known in Thailand since ancient times. This property of Kratom has the potential to save lives, and can be added to the long list of Kratom’s miraculous benefits, although of course more research needs to be done. Indeed, this was a Petri dish sort of experiment, and the next steps would be animal studies and then human studies, in order to obtain definitive proof that Kratom is anti-diabetic in humans.