The Risk Of Death From Kratom Is Over 1,000 Times Less Than The Risk Of Death From Synthetic Opioids And Opiates, And This Vanishingly Small Risk Is Only Due To Polydrug Abuse Involving Kratom
A group of scientists led by famous Kratom scientist Jack E. Henningfield have found that the risk of death from Kratom is over 1,000 times less than the risk of death from synthetic opioids and opiates in a study titled ‘Risk of death associated with kratom use compared to opioids‘.
In the introduction to this study there is some very important information, including that 16 million Americans use Kratom, and even that is a conservative estimate. Further, out of the 43 supposed Kratom deaths that the FDA lists, the concentration of Mitragynine in the blood was all over the place, anywhere from 5.6-29,000 ng/ml, bringing into question any link between Mitragynine levels and toxicity, i.e. casting doubt over whether Mitragynine is toxic at all even in extremely high doses. Adding to that point is the fact that animal studies have found that only doses of Mitragynine that are hundreds of times higher than what humans take are toxic.
Critically, after careful analysis of all of the literature and ‘kratom related deaths’, this study found that Kratom itself has never caused a death in history, and the only risk associated with Kratom is if people combine it with other drugs.
Ultimately, through statistical analysis this study conservatively estimates that Kratom is over 1,000 times less deadly than synthetic opioids and opiates, and over 100,000 times less deadly than Heroin. The vanishingly small risk that remains is due to combining Kratom with other drugs.
Therefore, when it comes to someone who is just taking pure Kratom and no other drugs, there is zero risk of death, and equivalently synthetic opioids and opiates are infinitely more deadly than Kratom.
On a final note, aside from the major finding that Kratom is over 1,000 times less deadly than synthetic opioids and opiates, this paper also points out that Kratom is saving lives. Indeed, synthetic opioids and opiates are killing over 50,000 Americans per year, and that number would be much higher if Kratom were banned, since a significant fraction of the 16 million Americans who use Kratom would likely start using synthetic opioids and opiates again.
Putting it all together, unlike drugs, Kratom does not really have a death rate. Rather, Kratom has a life rate.