The Kratom Genome Has Been Sequenced, Revealing That Kratom Is Genetically Most Closely Related To Coffee, In Addition To Sharing Similar DNA With Chocolate, Grapes, And Tomatoes
A group of scientists from universities across the world have sequenced the Kratom genome for the first time in a scientific study titled ‘The Mitragyna speciosa (Kratom) Genome: A resource for data-mining potent pharmaceuticals that impact human health‘.
This is an extremely groundbreaking endeavor, since it gives a better understanding of Kratom than ever before, via revealing what Kratom’s DNA is comprised of. In-fact, this is a major leap forward that will undoubtedly lead to a much better understanding of how Kratom’s alkaloids work, and the potential pharmaceutical applications of Kratom.
I could probably write 10 articles based on this one scientific paper, since there is so much going on with it. Some key points include that Kratom is most closely related to Coffee, as seen in the above chart. This means that Kratom and Coffee share a lot of the same DNA, which is perhaps not surprising considering that both Kratom and Coffee are relatively safe medicinal plants that produce stimulant effects.
Simultaneously, Kratom is also closely related to Tomatoes, Grapes, and Chocolate, although these don’t share quite as much DNA as Coffee and Kratom.
Aside from this extremely interesting result, via sequencing Kratom’s genome, these scientists have gone a long way towards figuring out how Kratom’s alkaloids are produced, i.e. how Kratom biosynthesizes its alkaloids, which has practical applications for producing Kratom’s alkaloids synthetically.
Overall, the scientists conclude “Access to an annotated genome assembly of M. speciosa ‘Rifat’, coupled with access to gene expression profiles, will facilitate discovery of alkaloid biosynthetic pathway genes and heterologous production of bioactive alkaloids. Furthermore, the M. speciosa genome will aid in improving our understanding of the evolution of plant specialized metabolic pathways and provide a resource to understand genetic diversity in M. speciosa.”